Acetamide, 2-[[7-(3,4-dimethoxyphenyl)-2-quinoxalinyl]amino]-N-methyl-
BQR695
CAS: 1513879-21-4
Molecular Formula: C19H20N4O3
Acetamide, 2-[[7-(3,4-dimethoxyphenyl)-2-quinoxalinyl]amino]-N-methyl- - Names and Identifiers
Acetamide, 2-[[7-(3,4-dimethoxyphenyl)-2-quinoxalinyl]amino]-N-methyl- - Physico-chemical Properties
| Molecular Formula | C19H20N4O3 |
| Molar Mass | 352.39 |
| Density | 1.250±0.06 g/cm3(Predicted) |
| Boling Point | 607.1±55.0 °C(Predicted) |
| pKa | 15.14±0.46(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| In vitro study | Treatment with 0.5 μM of either KAI407 or BQR695 causes GFP-PH Osh2 to redistribute to the parasite plasma membrane, consistent with depletion of intracellular PI4P upon inhibition of PfPI4K function. BQR695 shows no evidence of toxicity against mature red blood cells (RBCs), induces a schizont-stage arrest indistinguishable from that observed in imidazopyrazine-treated parasites and exhibits cross-resistance with the imidazopyrazine-resistant lines. |
Acetamide, 2-[[7-(3,4-dimethoxyphenyl)-2-quinoxalinyl]amino]-N-methyl- - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.838 ml | 14.189 ml | 28.378 ml |
| 5 mM | 0.568 ml | 2.838 ml | 5.676 ml |
| 10 mM | 0.284 ml | 1.419 ml | 2.838 ml |
| 5 mM | 0.057 ml | 0.284 ml | 0.568 ml |
Last Update：2024-01-02 23:10:35
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CAS: 1513879-21-4
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CAS: 1513879-21-4
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Mobile: 18021002903
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